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Press Releases
August 11, 2010 PolyMedix Successfully Completes Phase 1B/2 Heparin Dose-Ranging Study with PMX-60056 Heptagonist

PMX-60056 Reverses Surgical Levels of Heparin

Re-Anticoagulation achieved, then successfully reversed with PMX-60056

Data will guide dosing for Phase 2 clinical trial in surgical patients
July 07, 2010 POLYMEDIX RECEIVES NIH GRANT TO DEVELOP NEW ANTIMICROBIALS FOR THE TREATMENT OF MALARIA
Up to $4 Million available over five years
June 08, 2010 PolyMedix to Review Results from Recent Phase 1B LMWH Reversal Clinical Study with Heptagonist PMX-60056
Webcast Scheduled for Wednesday, June 9th at 4:00 PM ET
June 03, 2010 PolyMedix Successfully Completes Phase 1B Clinical Study To Reverse Low Molecular Weight Heparin with PMX-60056
PMX-60056 met safety and efficacy endpoints regarding the reversal of LMWH
June 02, 2010 PolyMedix to Present at the Noble Financial Equity Conference
May 27, 2010 PolyMedix Receives National Science Foundation Grant to Support Development of Antimicrobial Sutures
12th Grant or Research Contract Received by PolyMedix To Date
May 26, 2010 PolyMedix to Present at the UBS Global Specialty Pharmaceuticals Conference
Presentation June 3, 2010 @ 3:00 PM
May 10, 2010 PolyMedix to Present at the Rodman and Renshaw Annual Global Investment Conference
April 28, 2010 PolyMedix Initiates Phase 1B/2 Dose-Ranging Clinical Study With PMX-60056 to Reverse Heparin
Second heparin-reversal study follows successful pilot efficacy study
April 06, 2010 PolyMedix Reschedules Webcast for Wednesday, April 7 at 10:00 AM
Management to Review Results from Phase 1B Clinical Study with Novel Antibiotic, PMX-30063
April 01, 2010 PolyMedix Secures $14 Million Credit Facility and Files Shelf Registration Statement
March 30, 2010 PolyMedix Successfully Completes Phase 1B Clinical Study With Novel Antibiotic PMX-30063
Study showed multiple doses of PMX-30063 to be safe and well-tolerated Phase 2 clinical trial in Staph patients planned for 2Q 2010
March 18, 2010 PolyMedix Initiates Phase 1B Clinical Study With PMX-60056 To Reverse Low Molecular Weight Heparin
PMX-60056 is the first ever agent taken into clinical trials for LMWH reversal
March 11, 2010 PolyMedix Presents PMX-30063 Antibiotic Data at 8th World Congress on Trauma, Shock, Inflammation and Sepsis – TSIS 2010
Session on Bacterial Drug Resistance, Superbugs, and the Need for New Antibiotics
March 08, 2010 PolyMedix to Present at The Roth 22nd Annual Growth Stock Conference
February 09, 2010 POLYMEDIX announces planned milestones for 2010
On-Track to Initiate 4 Clinical Trials
February 02, 2010 PolyMedix to present at the 12TH annual BIO CEO conference

This press release contains forward-looking statements made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995 that involve risks, uncertainties and assumptions that could cause PolyMedix’s actual results and experience to differ materially from anticipated results and expectations expressed in these forward looking statements. PolyMedix has in some cases identified forward-looking statements by using words such as “anticipates,” “believes,” “hopes,” “estimates,” “looks,” “expects,” “plans,” “intends,” “goal,” “potential,” “may,” “suggest,” and similar expressions. Among other factors that could cause actual results to differ materially from those expressed in forward-looking statements, PolyMedix’s compounds may not enter or successfully complete clinical testing, or be granted regulatory approval to be sold and marketed in the United States or elsewhere. A more complete description of these risk factors is included in PolyMedix’s filings with the Securities and Exchange Commission. You should not place undue reliance on any forward-looking statements. PolyMedix undertakes no obligation to release publicly the results of any revisions to any such forwardlooking statements that may be made to reflect events or circumstances after the date of this press release or to reflect the occurrence of unanticipated events, except as required by applicable law or regulation.

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